Welcome to visit my research domain. My research is primarily in the areas of Bioinformatics, Biostatistics and Statistics Genetics. I’m currently developing statistical methods and software tools for biomedical applications of next-generation sequencing technologies (e.g. 454, Solexa, SOLiD).  I’m interested in solving statistics and informatics problems in genome assembly, genetic and epigenetic polymorphism discovery, and cancer mutation profiling studies. As part of my research in the past years, I’ve developed several bioinformatics tools that are available at the follow links. If you have any questions about these tools, please feel free to contact me at whduke dot gmail dot com.